- She appears on the TV series Star Trek: The Next Generation with Patrick Stewart.
- Both she and X-Men co-star Halle Berry have played Bond girls in the James Bond franchise. Janssen played femme fatale Xenia Onatopp in 1995's GoldenEye (where she co-starred opposite Alan Cumming).
- She had previously acted with Jason Flemyng in the 1998 action-horror film Deep Rising.
- She is a Dutch actress born on November 5, 1964 in Amstelveen.