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|Real Name||William Stryker Jr.|
Colonel William Stryker
Major William Stryker
|Species||Human (Homo sapiens)|
|Date of Death||2003 (original timeline)|
|Birth Place||United States of America|
|Team|| Team X|
Department of Domestic Security and Defense
|Movie|| X2: X-Men United|
X-Men Origins: Wolverine
X-Men: Days of Future Past
|Game||X-Men Origins: Wolverine|
|Comic|| X2: X-Men United: The Movie Prequel: Wolverine|
X2: X-Men United: The Movie Prequel: Nightcrawler
|Status|| Deceased (original timeline)|
Alive (revised timeline)
|Portrayed by|| Brian Cox (X2: X-Men United, X-Men: Days of Future Past; latter via archive footage from X2)|
Danny Huston (X-Men Origins: Wolverine)
Josh Helman (X-Men: Days of Future Past, X-Men: Apocalypse)
- “Mutants, I don't hate them. I just know what they can do. You don't realize this but we are at war. I took an oath: Protect this country. My name is William Stryker, and I am not a monster. I'm simply a patriot.”
- ―William Strykersrc
William "Bill" Stryker Jr. is a covert operations specialist and military scientist. Known for his anti-mutant stance, he worked tirelessly over several decades to develop solutions to what he saw as the "mutant problem". Ironically enough, he himself was part of the problem as only males can pass the mutant gene to their offspring.
During the Vietnam War, William Stryker was an experienced helicopter pilot and flew many Black Ops missions into the jungles of North Vietnam.
In 1973, Major William Stryker was a personal assistant and bodyguard of Bolivar Trask. He is first seen in an American airbase in Vietnam where he attempts to subjugate several mutants including Havok and Toad to be brought in for experimentation at a Trask Industries laboratory. Mystique poses as an army colonel to interrogate Stryker's intention, and subdues him, taking the mutant privates back to America. Stryker tries to stop them escaping, to no avail.
Stryker later accompanies Trask to the Paris Peace Conference held between the U.S. and Vietnam military leaders. Whilst there, Trask unveils to the generals present the prototype specs for the Sentinels and the mutant detection devices to be fitted into each of them, until he detects Mystique's presence in the room. Mystique reveals her true form and knocks out everyone in the room, subduing them, except for Trask.
During the Paris Peace Conference, Mystique reveals her true identity, dispatching the guards and shoots Trask dead. However, Mystique was quickly subdued by William Stryker, who recovers, tasers her, and brings her in for experimentation. She went through countless experiments that torture her. The killing caused governments worldwide to fear Mutants and initiate the Sentinel Program. Eventually Mystique's DNA was mapped, reverse engineered, replicated, and installed into the most recent Sentinels, wherein the nature of her powers are distilled and used to enable the Sentinels' capability to imitate and adapt any mutant powers to counter their abilities. Trask becomes a martyr for the anti-mutant movement, with Stryker spearheading the Sentinel initiative's development in his honour.
X-Men Origins: Wolverine Prologue
Some months after Trask's death, Stryker approaches James Logan and Victor Creed, after the mutant pair survived execution by firing squad. As he enters their cell, Stryker asks them to join his special team of mutants he is assembling, Team X, as a way out of imprisonment. Victor and Logan accept and join other mutants - Wade Wilson, Agent Zero, Chris Bradley, Fred Dukes, and John Wraith - on covert missions throughout the world.
During one of their missions, while under Stryker's command, Team X is sent to search for and retrieve a mysterious meteorite - later discovered as Adamantium - from a diamond trafficking operation in Lagos, Nigeria. They attack a compound there and after defeating the compound's security forces, they obtain a mysterious rock - later discovered as a meteorite fragment that fell from the sky as a meteor - from the compound's leader and discover that it originates from a remote village.
Upon arriving at the village, Stryker and the team them interrogated nearby villagers to see if there were any other meteorites and are informed that the rock fell from the sky as a meteor. Stryker wants more information and has Wade Wilson interrogate in his place because he speaks the language. When they threatened the village as to where the meteorite came from, the village chief refused to tell Stryker the origins of the meteorites, as they believe them to be sacred. After receiving no further answers, Stryker orders his team to attack the villagers by first ordering Victor to kill the chief. The whole village descended into chaos as Stryker's team started killing the civilians. When the mutants begin attacking a nearby village, Logan, however, stops them before they can do so.
After a brief argument with Victor, Logan quits the team, saying he can't kill innocent people as he was disgusted by the murders committed by his teammates, Stryker's willingness to kill innocent civilians, and Victor's acceptance of this. He promptly leaves and abandons Victor and the group before walking into the night and leaving, while ignoring Victor's calling out to him. With his departure, Team X disbands. Eventually, after everyone else left, only Agent Zero and Victor stayed faithful to Stryker.
X2: X-Men United Prologue
When William Stryker discovers that his son, Jason, is a mutant, he sends him to Xavier's School for Gifted Youngsters in the hopes of ridding his mutation, regarding it as a disease that needed to be cured. Xavier had no interest or belief in "curing mutants, which angered Stryker. A furious Stryker was then encouraged to embrace Jason's mutation, and withdrew Jason from the programme. Over the next year, Jason grew increasingly angry, resentful, and vindictive towards his parents and blamed them for his condition, to which he began to use his powers to torment them, planting horrific illusions and images in their minds. Unable to handle the torturous illusions, Stryker's wife eventually committed suicide by applying a power drill to her left temple, and drilling into her own brain in an attempt to "bore the images out". Stryker then gave his son a lobotomy to make him more docile and kept him cryogenically frozen. Unable to cope with his wife's death, Stryker vowed to eliminate all of mutantkind.
During the next six years following Team X's disbandment, Stryker was promoted to Colonel and made Agent Zero and Victor his henchmen in order to abduct various mutants for his upcoming Weapon X project - Weapon XI. During this time, Victor captured Emma Silverfox, the sister of Kayla Silverfox, for experimentation. Stryker then gave Kayla the task of keeping an eye on Logan, who had left Team X and went back to Canada.
One day, Zero and Stryker visit Logan while at work to infrom him that Bradley and Wade were killed recently. Before doing so, Stryker asks Logan if he remembers Agent Zero, with Logan responds by asking Zero if he's still shooting first and asking questions later. Zero responds by pulling out his concealed gun, shooting Logan's Cigar, and, after putting away his gun, asks Logan a follow-up question as to if he's still chewing on cheap cigars. As Stryker tells Logan he has a job for him, Logan tells Stryker he already has a job. Zero humorously questions Logan's job payment as a lumberjack by asking if it pays 18 grand a year. Logan corrects him by saying his pay is actually 18.5 grand a year, before saying he hasn't had to kill anybody lately. Zero asks if Logan is starting to miss it, Logan, getting irritated, say now he is, before Stryker breaks them up, ordering Zero to the car, which he proceeds to do.
Victor agreed to go along with Styker's plan to trick Logan into agreeing to have adamantium bonded to his skeleton by claiming that Victor had gone rogue and Kayla Silverfox, Logan's' girlfriend, is supposedly killed in order to lure Logan for the adamantium process of the Weapon X program.
2 days later, after being brutally beaten by Victor, Logan wakes up in an emergency room, where Stryker happens to be present. Styker tells Logan he can help him exact revenge on Victor with an experimental procedure. Logan agrees to go through with it, but also warns that he is bent solely for revenge.
Prior to the adamantium procedure, Logan asks for new dog tags with the name "Wolverine" on them - a reference to the story Kayla told him. Stryker binds Logan's bones with adamantium, making him virtually indestructible by grafting the metal compound onto his entire skeletal structure. Logan flatlined afterwards, but after a few moments, he resuscitates. After the process was successful, Stryker ordered Logan's memory to be wiped to protect the location of the Alkali Lake facility and so that his DNA could be used for an upcoming project. Logan escapes the facility after overhearing Sryker's plans. Stryker orders Zero to pursue him - eventually tracking him to a barn belonging to an elderly couple who had taken Wolverine in. After Zero failed in his mission, Wolverine took his receiver and announced his plans for killing the Colonel after killing Victor, as revenge to Stryker.
General Munson when confronted Stryker and tried to shut Weapon X down, and forced to halt To the Colonel's meant experimentations. The official claims that Stryker has gone too far as a result of his anger at the death of his wife. It is then revealed that this is due to his son, who turns out to be a mutant, indicating the source of his hatred of the mutant race. Learning of Stryker's son and believing that he was too emotionally close to the situation, Stryker kills General Munson.
After Logan arrives on the Island, he finds Stryker, who tells him about Deadpool, and reveals that Kayla (present on the island) wasn't really killed; as Silverfox is revealed to be alive and was reluctantly working for Stryker. As Victor is watching through the window from a nearby room, Wolverine was told that Victor and Stryker were subsequently working together to capture various mutants, culminating in tricking Wolverine into agreeing to have adamantium bonded to his skeleton by claiming that Victor had gone rogue and had killed the woman Wolverine loved. She had at some point been recruited by Stryker for the purpose of seducing Logan and creating an incident where he was compelled to join the Weapon X program and participating in the adamantium procedure - in this case, her faked death. With Victor Creed's assistance, her murder was faked with hydrochlorothiazide for Stryker, so he could trick Logan into participating in his Weapon X project. When Stryker claimed that Logan and Kayla's love was never real, she nods her head in denial, but Stryker silently threatens her with a concealed gun. After hearing how Kayla was working for Stryker, Logan left the facility to move on with his life.
Shortly after Logan's departure, Kayla confronted Stryker. She demanded he release her sister, who was also being held at the facility, only to be placated by him and told to wait. Then, Victor arrives and becomes angry at Stryker, both for letting Logan go and for reneging on their deal to bond adamantium to his body and demanded the adamantium procedure. The animosity between the Victor and James was made even worse when Stryker revealed that, contrary to his deal with Victor, he cannot merge adamantium to his skeleton because it would kill him as his healing factor is less powerful than Logan's, and isn't strong enough to allow him to survive the process. Kayla tried to persuade Victor that Stryker was only using them. After Logan returned to save Kayla from being killed by Victor, and defeated him, Logan and Kayla prepared to free the captured mutants. This enticed Stryker to order Weapon XI's activation, despite the bonding process being incomplete.
After freeing the imprisoned mutants, while leading them out of the facility, Logan, and the mutants are stopped and confronted by Weapon XI, Deadpool - now controlled by Stryker. Logan puts forth his best effort, but is pinned down. Just as Weapon XI is about to decapitate him, (at the command of Stryker), Victor shoves him away, and both of them fall into the reactor. Victor catches Logan, explaining the only reason he saved him was so he could kill him himself.
After Weapon XI failed to kill off Wolverine, and his mutant prisoners had escaped, Stryker readied a revolver, filled with adamantium bullets, which are the only things that can supposedly 'hurt' Logan. Carol Frost tried to convince Stryker that they won't work on Logan, due to the mutant's rengerstivenhealing. But Stryker claims Ed that, alothugh Logan's brain may physically heal, his memories "will never grow back". This claimed reveled that Stryker was attempting to take away Logan's memories, if the the latter can't be killed.
As Logan and Kayla were preparing to leave the island, Stryker walked up behind them and shot Logan with adamantium bullets in the back. In a feral rage, he turns and sprints at Stryker, eventually jumping after him. As he is in mid-leap, Logan is shot in the head twice by Stryker with adamantium bullets, and falls to the ground, unconscious - damaging his brain, causing amnesia, and forcing Logan to lose much of his long-term memory. Although the physical injury heal, his memories seem to be permanently gone.
This knocked Logan out long enough for Stryker to go after Silverfox but she turned the tables by touching his ankle. At first she forced him to put the gun to his own head but killing him was not her style or in her nature. Instead, she commanded him to drop the gun, walk until his feet bleed, and then to walk some more by saying "walk until your feet bleed...then keep walking." Stryker unwillingly proceeds to do so. Later, Stryker - exhausted and worn - is seen wandering down an isolated road. Then, military police in military vans arrived and approached the exhausted Colonel. An officer emerges and states that Stryker is wanted for questioning about his connection with General Munson's murder, which Stryker was charged of.
To Be Added
To be added
Between X-Men and X2: X-Men United
After Magneto's defeat at Liberty Island and his capture by the authorities, William Stryker was notified and had Magneto transferred into the hands of the Department of Domestic Security and Defense. His department had dealt with the incarceration of mutant subjects before, so they constructed a plastic prison to keep Magneto contained without an ounce of metal that could aid in his escape.
Stryker also used the rare opportunity of having Magneto in his custody, being well aware of his connection with Charles Xavier, to interrogate him via the use of the mesmeric serum of his son, Jason Stryker, to discover more about their past together. Through Magneto, Stryker became aware of the existence of Xavier's Cerebro in the subbasement of the X-Mansion and what it was capable of. Seeing the possibility to wipe out mutants for good, Stryker set about formulating a new plan.
Stryker re-emerged from hiding to enact his new agenda, by using a fluid secreted from Jason's brain to control mutants, such as Nightcrawler and Lady Deathstrike. He brainwashed Kurt Wagner into assassinating President McKenna to justify an attack on the X-Mansion. However, this having failed, Stryker instead capitalizes on the recent assassination attempt to convince the President to authorize an operation to infiltrate the X-Mansion, claiming that it is a mutant training facility responsible for the attack. Stryker expects Xavier to investigate the assassination attempt, and orders Yuriko to intercept Charles Xavier en route to meeting Magneto, also capturing Cyclops in the process. He eventually brainwashes Cyclops in the same manner he had Yuriko, Wagner, and Magneto.
During the evening, Stryker's military forces led by Sergeant Lyman invade the X-Mansion. While there, his soldiers are able to capture several students (though most flee). Wolverine stays behind to confront the attackers but is shocked to discover that they are being led by William Stryker. Stryker, himself surprised to see Wolverine - the man he had worked with, experimented on, and severely injured decades earlier - in the mansion, reveals that he knows much about Wolverine and wishes for him to come with the military to discuss it. Before Wolverine answers, Iceman is able to create a wall of ice between them. Before leaving, Stryker and his soldiers infiltrate the Mansion's subbasement in order to extract more information about Cerebro.
At the Alkali Lake facility (the underground portion of which he still used following the abandonment and destruction of the main level), he reveals to Xavier that he was able to brainwash the mutants by extracting fluid from his son Jason's brain and injecting it into the back of their necks. After Xavier learns that Stryker is the mastermind behind an assassination attempt on the President by a brainwashed Nightcrawler. Stryker then puts his plan into action, and gains control over Professor Xavier through his son, Jason Stryker, who is able to project powerful visions in the mind, blinding a person to reality. Jason (in the form of a young girl) instructs Professor X to use Cerebro to find all existing mutants and kill them. Magneto, Mystique, and the remaining X-Men stage their assault on the facility, by having Mystique infiltrate disguised as Wolverine. Stryker orders his guards to let "Wolverine" in, as he believes his experiment has finally decided to come home. Somehow Mystique's disguise doesn't fool Colonel Stryker. Mystique quickly incapacitates the soldiers and manages to take control of the control room, opening up the main gates so that the X-Men can enter the Alkali Lake Facility.
Magneto, wearing a helmet designed to shield against telepathic attacks, is able to reach Xavier while the X-Men are incapacitated by the psychic assault, but then has Jason make Xavier use Cerebro II to kill ordinary humans. Which Stryker is shocked that Cerebro II is turned against him. At his direction, Mystique impersonates Stryker and instructs Jason of a change in plans - to kill all humans, which Jason then communicates to the brainwashed Xavier.
Wolverine runs off on his own to look for Stryker. He finds Stryker in an adamantium smelting room along with Lady Deathstrike. After Stryker leaves, Wolverine attempts to follow him but is attacked by Deathstrike. A battle of blades ensues, which results in Wolverine pumping Deathstrike full of molten adamantium metal, killing her. Stryker attempts to escape, but Logan confronted him on a landing pad after defeating Lady Deathsrike. Stryker was stabbed through the arm by his adamantium claws and Logan scolded him for "taking his life", although Stryker claimed that he apparently volunteered to have the adamantium placed in his skeleton. Stryker attempts to bargain with Wolverine by offering him a chance to come with him and restore his memories by helping the mutant learn more about his forgotten past. Wolverine refuses and chains the wounded Stryker to the helicopter wheel, saying that if the X-Men die, Stryker will too.
After Dark Cerebro is reprogrammed, Stryker is shown to be in the same pain as every other human much to his shock. Later on, Magneto and Mystique come across Stryker once again, and ties Stryker to a concrete wall with the metal chain. Magneto, Mystique, and Pyro use the helicopter as an escape vehicle and leave Stryker to die. When the X-Men and the students make their way back to the Blackbird, Logan comes face to face with Stryker one last time, who asked "Who has the answers, Wolverine? Those people? That creature in your arms?". Looking at the young mutant, Artie Maddicks, that he was carrying to safety, Wolverine puts him down, dropped the dog tags Stryker fashioned for him years earlier and informs Stryker that he would "take his chances with him" and left him to die, by leaving him at the mercy of the collapsing dam. As Wolverine walks away, Stryker bellows after him that "one day someone will finish what I've started. One day!" Given his immobilised status, Stryker presumably dies when the nearby dam bursts. Wolverine and [Artie Maddicks were the last two people to see Stryker.
According to Charles Xavier, William Stryker was not simply drowned when the dam at Alkali Lake burst, but was disintegrated by the sheer force of the water pressure pummeling his body, a fate that would have beheld Jean Grey, if her powers did not shield her in a cocoon of telekinetic energy.
Stryker later accompanies Trask to the Paris Peace Conference held between the US and Vietnam military leaders. Whilst there, Trask unveils to the generals present the prototype specs for the Sentinels and the mutant detection devices to be fitted into each of them, until he detects Mystique's presence in the room. After Mystique subdues most of the guards in the room and prepares to kill Trask, Stryker tasers her and attempts to bring her in, until Professor X, Magneto, Wolverine and Beast intervene, and Magneto uses his powers to attach the tasers onto him instead.
Whilst he is incapacitated by his own taser, Logan looks down at Stryker and experiences a flashback to Stryker's involvement in Weapon X. After recovering and removing the taser from his body, Stryker spares a fleeting glance at Wolverine's bone claws, before running out of the conference room. Later, Stryker is present at Trask's side when he unveils the Sentinel designs to President Nixon in the Oval Office, as a response to the impending mutant threat posed by Magneto and Mystique.
He then accompanies Trask to the public demonstration of the Sentinels outside the White House, expressing surprise at the Sentinels' remote activation at the hands of Magneto. Once the Sentinels begin attacking the humans at Magneto's behest, Stryker shepherds Trask into the White House's Presidential bunker for their safety. Whilst in the bunker, Trask is alerted to the presence of a mutant inside the bunker, prompting the Secret Service agents and Stryker to pull out their weapons to subdue Mystique. Magneto uses his metal powers to cause their guns to hit the roof, prompting Stryker to pull out his plastic gun, which a disguised Mystique takes off him during the commotion. Magneto pulls the bunker out of the White House in an attempt to kill Nixon, and Mystique uses Stryker's plastic gun to shoot Magneto in the neck, incapacitating him.
Mystique later poses as Major Stryker to fish Wolverine out from the Potomac River, where he was flung by Magneto, and states that she will take him under her care.
After the destruction of the X-Mansion, a chopper descends to the ground. Moira MacTaggert approaches them, thinking they are part of another agency, until the leader steps out and removes his sunglasses. It's William Stryker. Raven notices him and tries to warn everyone, but Stryker orders his men to fire a sonic blast that incapacitates everyone, except for Scott Summers, Jean Grey, and Nightcrawler. Jean manages to keep them hidden by manipulating the mind of one of Stryker's men. Stryker captures Raven, Moira, Hank, and Peter. Nightcrawler teleports himself, Scott, and Jean into their chopper, but he cannot get anyone out because of the electrical lining within.
Stryker takes everyone to his facility and traps Moira and the mutants in a room. Hank has re-mutated to Beast since he left his meds at home. Stryker then gets everyone's attention, and crudely adressed Mystique, who then addresses him as "Major Stryker", but he corrects her, saying it's "Colonel Stryker" now. Moira objects to him capturing her and the mutants, as well as pointing she's a CIA agent, but Stryker already knows this. He explains the worldwide anomalies, regarding the nukes that were released and the signs came from the X-Mansion, and demands to know where Charles Xavier is. Moira and the others tell Stryker that they don't know, and Moira informs him that their is an enemy more powerful than Xavier that Stryker needs to worry about. Strker then leaves, ignoring her warnings.
Charles, thanks to Apocalypse enhancing his telepathic powers, sends a message to everyone on the planet, but Charles manages to get a hidden message to Jean to help her find where he's located. After Charles broadcasted his message to the world, Stryker then confronts his prisoners, noting that he recognizes that voice belonging to Charles Xavier, and once again asks them where the telepath is. But once again, they all inform them that they don't know.
When Wolverine gets loose thanks to Jean Grey and kills Stryker's men, Stryker makes his escape.
Following Apocalypse's defeat, Moira MacTaggert has Stryker arrested for his recent crimes: assaulting and kidnapping her, a federal officer, and for issuing unruly punishment to minors. Stryker warns her that mutants should not be trusted, and when that day comes, she better hope he's there when it happens. Moira watches as Stryker is taken away, and nonchalantly ignores his words on how untrustworthy mutants are.
Since the future changed significantly due to the repercussions of Wolverine time travelling back to 1973 in ensuring the Sentinel program is cancelled, one of the secondary results of the time travel is that all the X-Men (excluding Havok) are still alive. This means that the events wherein Stryker kidnapped Xavier and the affair at Alkali Lake (where Jean Grey sacrificed her life to protect the X-Men from the Alkali Lake dam bursting its banks), never occurred. Another result of the timeline being changed, is that Team X was never formed. Thus, Stryker never ordered Victor Creeed to hunt down and kill members of Team X, in order for their DNA to be used as part of the Weapon XI project, which no longer existed in the revised timeline.
Stryker's ultimate fate as of 2023 is currently unknown.
A profound mutant-hater, William Stryker had served and protected his country for decades until he concluded that the main threat against the United States and its interests was not from opposing countries but rather from within. Thinking the greatest threat to the world mutants, Stryker became extremely paranoid and was dedicated to advancing the military to combat with these mutant problems should the need ever arise to, going by means of illegal experimentation on mutations. Though he has prioritised global and national security, Stryker has single-handedly caused social upheaval by implicating mutants in the assassination to the President of the United States in an attempt to turn them into public enemies so his attempted genocide on their species would be considered more acceptable. Stryker was also willing to kill his superiors if they went against his plans by murdering General Munson when he threatened to close the Weapon X Program.
Part of this intense hatred for mutants comes from Stryker birthing one himself. His son, Jason blamed him for his mutation as it was usually passed along through the Y (male) chromosome. Furthermore, when he sent Jason to Charles Xavier's School for Mutants, Stryker believed his son was to be cured, only to discover that mutation was not disease and this enraged Jason further, to the point where he tormented his mother and father to no end until Stryker's wife eventually committed suicide. Now with a personal incentive, Stryker's hatred only expanded until he set his goals on killing every mutant on Earth. Despite his hatred, though, Stryker found the usefulness of using mutants, at least those who he could control such as Laday Deathstrike, Nightcrawler and Cyclops. His basis on this was thinking that the only effective way to kill mutants was with mutants by building the ultimate mutant-killer - Weapon XI. However, the original Team X was not mind-controlled with Sabretooth and Agent Zero being of their own free mind and will but it was presumably Wolverine, Wraith, Dukes, Wade and Bradley leaving that prompted Stryker to using mind control. Having studied mutants for years, he knew how to counteract with different threats opposed by individual mutants unique and varying powers such as building a plastic prison to contain Magneto, a device that prevents Professor X from taking control of anyone's mind and giving Lady Deathstrike an adamamtium skeleton and regenerative healing factor that was able to match and evenly duel with Wolverine, including adamantium nails similar to Logan's claws
- General Munson - Former Sponser and Ally turned Victim
- Deadpool - Former Teammate and Experiment
- Lady Deathstrike - Experiment and Former Bodyguard
- Agent Zero - Former Teammate and Former Bodyguard
- Lyman - Former Subordinate
- Carol Frost - Former Subordinate
- Abraham Cornelius - Former Subordinate
- Sabretooth - Former Teammate and Ally turned Enemy
- Pyro - Enemy
- Kayla Silverfox - Former Subordinate and Enemy
- Emma Silverfox - Kidnap Victim and Enemy
- Gambit - Kidnap Victim and Enemy
- Artie Maddicks - Kidnap Victim and Enemy
- Cypher - Kidnap Victim and Enemy
- Chris Bradley - Former Teammate
- Fred Dukes - Former Teammate
- John Wraith - Former Teammate
- Bolivar Trask - Former Superior
- Wolverine - Experiment and Enemy
- Mystique - Kidnap Victim and Enemy
- Beast - Kidnap Victim and Enemy
- Quicksilver - Kidnap Victim and Enemy
- Moira MacTaggert - Kidnap Victim and Enemy
- Havok - Enemy
- Toad - Enemy
- Ink - Enemy
- Daniels - Enemy
- Professor X - Enemy
- Magneto - Enemy
- Nightcrawler - Enemy
- Cyclops - Enemy
- Jean Grey - Enemy
- Jubilee - Enemy
- Storm - Enemy
- Iceman - Enemy
- Rogue - Enemy
- Colossus - Enemy
- Shadowcat - Enemy
- Stryker is one of only two people who can see through Mystique's disguise, the other being Wolverine. Stryker sees through Mystique's abilities whilst she is imitating Wolverine to enter Stryker's base at Alkali Lake. He states that "if there's one thing I know better than anyone, it's my own work".
- William Stryker is the second-most recurring villain in the X-Men film series, second only to Magneto. Both men believe that the motivations behind their actions are for the greater good.
- Despite his apparent hatred for mutants, he frequently operates with military teams composed entirely of mutants. Examples are his formation of Team X, his creation of Deadpool, his control over Lady Deathstrike and the fact that he decided not to kill his son for being a mentally-ill mutant and for killing his wife.
- A notable discrepancy exists between the two portrayals of Stryker by Josh Helman and Danny Huston respectively; although Helman's incarnation is meant to predate Huston's, Helman only wears military decorations from the Vietnam War (1955-1975), whereas Huston wears decorations from the Korean War (1950-1953) and the Vietnam War.
- According to his military dogtags in Days of Future Past, William Stryker is a Protestant.
- In X-Men: Days of Future Past, Stryker has won the following military decorations (according to those apparent on his uniform):
- Silver Star (Ribbon) with "V" Valor Device
- Purple Heart (Ribbon)
- Meritorious Service (Ribbon) with "V" Valor Device
- National Defense Service (Ribbon)
- Vietnam Service (Ribbon) with Bronze Oak Leaf Cluster, indicating won twice
- Vietnam Campaign (Ribbon)
- Combat Infantry Badge
- Master Parachutist Badge (Army)
- Army Presidential Unit Citation
- His father, William Stryker Sr., has a minor role in X-Men: First Class. Stryker himself is mentioned by Xavier in passing, as his father was thinking about him during Xavier's meeting with the CIA.
- A deleted scene from X-Men: Days of Future Past presents an alternate take on Logan's recovery from the Hudson River at the end, wherein Stryker is asked what to call him, simply responding "Just call him... 'X' ", a reference to Logan's status as "Weapon X", the culmination of Stryker's mutant experiments to synthesize adamantium bonding to a mutant's exoskeleton to create the ultimate mutant soldier. Additionally, the Stryker that was featured during this alternate scene appeared to be the real William Stryker, and not Mystique posing as Stryker as was shown during the final scene of the theatrical cut.
- In X-Men: The Official Game, a mistake is made regarding Stryker's rank. Although he was referred to as a general in the game, the highest military rank he attained was that of colonel before his death in X2: X-Men United.
- In the comics, Stryker was a very different character from his film counterpart. He was a Christian televangelist instead of an army officer (though his comic book counterpart had a brief military stint) who hated mutants on a religious level based on his belief that all mutants are Satanic and are worthy of being exterminated in a holy war. He also founded a similarly minded para-military/terrorist hate group called the Purifiers for this purpose. This led to him being changed for the X-Men films to avoid any religious controversy.
- Originally in the comics Stryker was a one-time character that only appeared in God Loves, Man Kills graphic novel in 1982, but his success in X2 led to him and the Purifers being re-introduced into the mainstream comics.
- Stryker's film counterpart instead borrows elements from two other Marvel villains, Professor Andre Thorton, the man in charge of the Weapon X program, and Henry Peter Gyrich, (whom the film character Henry Gyrich was named after), who in the comics was a ruthless government official who sees mutants as very dangerous and uses his government resources to suppress them (as well as other superhumans).