- “Mutation: it is the key to our evolution. It has enabled us to evolve from a single-celled organism into the dominant species on the planet. This process is slow, and normally taking thousands and thousands of years. But every few hundred millennia, evolution leaps forward.”
- ―Charles Xaviersrc
X-Men was the first X-Men film to start the series. In 1994, 20th Century Fox and producer, Prawan Singh bought the film rights to the X-Men. Andrew Kevin Walker was hired to write, and James Cameron expressed interest in directing. Eventually, Bryan Singer signed on to direct in July 1996. Though not a fan of the comic, Singer was fascinated by the analogies of prejudice and discrimination offered by it. Filming took place from September 22, 1999 to March 3, 2000 in Toronto.
The story opens in a concentration camp in Auschwitz, Poland, 1944. Erik Lehnsherr is separated from his parents by the Nazis, which causes his powers to manifest. He manages to bend a metal gate apart with his ability of magnetism before being knocked out.
In the United States Senate, Senator Robert Kelly attempts to pass a "Mutant Registration Act", which would force mutants to publicly reveal their identities and abilities. Magneto begins his plans to level the playing field between mutants and humans. Meanwhile, Marie, now going by Rogue, runs away from her home in Meridian, Mississippi. She meets Wolverine in Laughlin City, Alberta, Canada. Suddenly, both of them are attacked by Sabretooth, a mutant and associate of Magneto's. Cyclops and Storm arrive to save Wolverine and Rogue and bring them to the X-Mansion. Professor Charles Xavier runs the facility, and leads a group of mutants who are trying to seek peace with the human race, educate young mutants in the responsible use of their powers, and stop Magneto from starting a war with humanity.
Abducted by Mystique and Toad, Senator Kelly is brought to Magneto on Genosha, who tests a Conversion Machine on him that artificially induces mutation, though Kelly manages to escape imprisonment with his new abilities. After an accident causes Rogue to use her powers on Wolverine, she is convinced by Mystique (disguised as Bobby Drake) that Xavier is angry with her and that she should leave the school. Xavier uses Cerebro to locate Rogue at a train station. Mystique infiltrates Cerebro and sabotages the machine. At the train station, Wolverine convinces Rogue to stay with Xavier but a fight ensues when Magneto, Toad and Sabretooth arrive to take Rogue. Arriving at Xavier's school, Kelly dissolves into a puddle of water when his mutation becomes unstable. The X-Men learn that Magneto intends to use Rogue's ability on himself to power his machine. Xavier attempts to use Cerebro to locate Rogue but falls into a coma. Jean Grey fixes it and uses Cerebro to find Magneto's machine on the Statue of Liberty, which Magneto intends to use on the world leaders who are meeting for a summit on nearby Ellis Island.
Just as the group arrives at the top of the statue and kills Toad, Magneto and Sabretooth incapacitate the group and continue with their plans. Magneto transfers his powers to Rogue, who is forced to use them to start the machine. Wolverine breaks free and initiates a fight with Sabretooth but is thrown over the side of the statue. Wolverine returns, and Cyclops, with Jean's help, blasts Sabretooth out of the statue. Storm and Jean use their abilities to send Wolverine to the top of Magneto's machine. With time running out, Wolverine attempts to stop the machine and save Rogue, but Magneto, now having regained some of his strength, halts Wolverine's claws. Cyclops manages to find a clear shot, wounding Magneto and allowing Wolverine to destroy the machine. Placing his hand to a dying Rogue's face, Wolverine succeeds in transferring his regenerative abilities to her. Professor Xavier recovers from his coma and the group learns that Mystique is still alive (after Wolverine stabbed her at Liberty Island) when they see her impersonating Senator Kelly on a news broadcast.
In an attempt to help Wolverine learn more about his past, Xavier sends him to a military base near Alkali Lake. Xavier visits Magneto in his Plastic Prison cell, and the two play chess. Magneto warns his friend that he will continue his fight, to which Xavier promises that he (and the X-Men) will always be there to stop him.
- Hugh Jackman as Logan/Wolverine
- Patrick Stewart as Charles Xavier/Professor X
- Ian McKellen as Erik Lehnsherr/Magneto
- Famke Janssen as Jean Grey
- James Marsden as Scott Summers/Cyclops
- Halle Berry as Ororo Munroe/Storm
- Anna Paquin as Marie D'Ancanto/Rogue
- Tyler Mane as Victor Creed/Sabretooth
- Ray Park as Mortimer Toynbee/Toad
- Rebecca Romijn as Raven Darkholme/Mystique
- Bruce Davison as Senator Kelly
- Matthew Sharp as Henry Gyrich
- Brett Morris as Young Magneto
- Rhona Shekter as Edie Lehnsherr
- Kenneth McGregor as Jakob Lehnsherr
- Shawn Roberts as David
- Donna Goodhand as Priscilla D'Ancanto
- John E. Nelles as Owen D'Ancanto
- Kevin Rushton as Stu
- Sumela Kay as Kitty Pryde/Shadowcat
- Shawn Ashmore as Bobby Drake/Iceman
- Katrina Florece as Jubilation Lee/Jubilee
- Alexander Burton as John Allerdyce/Pyro
- Matt Weinberg as Tommy
- Washington, D.C.
- Westchester, New York
- New York City, New York
- Meridian, Mississippi
- Laughlin City, Alberta, Canada
- Alkali Lake, Alberta, Canada
- Auschwitz, Poland
- Plastic Prison
- Anchorage, Alaska (mentioned)
- Canadian Rockies (mentioned)
- Niagara Falls (mentioned)
- Cyclops' Visor
- Magneto's Helmet
- Magneto's Costume
- Conversion Machine
- Wolverine's Dog Tag
- This is the only film, in the X-Men series to be mostly an original story; all the other films were loosely based on specific stories from the comic books.